HOW TO TEACH THE CONCEPT OF "PROTEIN FOLDING"

1. what the students need to know for getting this knowledge

KNOWLEDGE

aminoacid features and properties
Hydrohylic and hydrophobic interactions
Peptide bond and distances
levels of protein structure

COMPREHENSION

Water interaction. How water contributes to the folding.
weak bond interactions within aminoacids
Ramachandran (limitations…)

APPLICATION

how water contributes to the folding.

ANALYSIS
effects of mutations
SYNTHESIS

EVALUATION

g) disulfur bonds
i ) chaperons
k) dynamic of folding
n) no protein interactions: cofactor, metals, sugars, and so on…