HOW TO TEACH THE CONCEPT OF "PROTEIN FOLDING"
1. what the students need to know for getting this knowledge
KNOWLEDGE
aminoacid features and properties
Hydrohylic and hydrophobic interactions
Peptide bond and distances
levels of protein structure
COMPREHENSION
Water interaction. How water contributes to the folding.
weak bond interactions within aminoacids
Ramachandran (limitations…)
APPLICATION
how water contributes to the folding.
ANALYSIS
effects of mutations
SYNTHESIS
EVALUATION
g) disulfur bonds
i ) chaperons
k) dynamic of folding
n) no protein interactions: cofactor, metals, sugars, and so on…
page revision: 3, last edited: 14 Sep 2010 10:09